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Bitter orange is a currently available herbal stimulant used in some weight-loss supplements and is often called an ephedra substitute. The active ingredient in bitter orange has chemical properties and actions that are similar to ephedra and may be associated with similar adverse effects.

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Some first-generation diet pills proved risky to the heart. Still, the approval of four new drugs in the past two years means there are now more Some doctors recommend orlistat (Xenical, Alli)—which works by blocking fat absorption in the  

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